Acetic Anhydride → HCID 23312606, compound

HRID 1846450Notes

Reaction equation

HRID 1846450 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][C:3]=1[CH3:9].[C:10]([O-:13])(=O)[CH3:11].[Na+].[C:15](OC(=O)C)(=[O:17])[CH3:16]>C(O)(=O)C>[C:15]([O:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][C:10](=[O:13])[CH3:11])=[C:3]([CH3:9])[CH:4]=1)(=[O:17])[CH3:16]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 178194-Amino-m-cresolHCID 517045Sodium Acetate

Product 1

HCID 23312606HCID 23312606, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
125 °C

Procedure

4.66 g (37.5 mmol) 4-amino-3-methylphenol, 5.00 mL glacial acetic acid, 0.500 g (6.09 mmol) sodium acetate and 7.87 mL (83.3 mmol) acetic anhydride were combined and stirred for 1 h at 125° C. After cooling to RT, ice water was added to the reaction mixture. The precipitate formed was suction filtered, washed with water and dried under HV.

Workup

  1. temperatureAfter cooling to RT
  2. customThe precipitate formed
  3. filtrationfiltered
  4. washwashed with water
  5. customdried under HV

Sources & evidence

ORD record
ord-526dca703d27442e80ec308f8e3c46e7
Source dataset
uspto-grants-2015_02
Patent number
US08952014B2

Reaction notes

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