反应详情

20.4 g (80.7 mmol) 4-acetylamino-3-methyl-5-nitro-phenyl acetate in 100 mL semi-concentrated aqueous hydrochloric acid were refluxed for 2 h. Then the reaction mixture was evaporated down, the residue was triturated with acetone and suction filtered. After washing with acetone and diethyl ether the precipitate was dried under HV. The mother liquor was evaporated down, the residue was taken up in water and freeze-dried.

1. customThen the reaction mixture was evaporated down
2. customthe residue was triturated with acetone and suction
3. filtrationfiltered
4. washAfter washing with acetone and diethyl ether the precipitate
5. customwas dried under HV
6. customThe mother liquor was evaporated down
7. customfreeze-dried