Carbamimidic acid, methyl ester, hydrochloride (1:1) → HCID 178494256, compound

Participants

Reaction Steps

Under a nitrogen atmosphere 3.10 mL (27.0 mmol) dimethylmalonate, 3.00 g (27.1 mmol) o-methylisourea hydrochloride and 15.0 mL (80.8 mmol) sodium methoxide solution (30%) were refluxed for 1.25 h with stirring. The reaction mixture was cooled. The precipitate formed was suction filtered, washed and dried.

Provenance & Evidence