Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846471Generated: October 31, 2026

Cyclopropanecarboximidamide hydrochloride → HCID 178516636, compound

https://huagongshe.com/reaction/1846471

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarboximidamide hydrochlorideHCID 2781916—
ReactantDimethylmalonatHCID 6946994—
ReactantSodium MethoxideHCID 10942334—
ProductHCID 178516636HCID 178516636—

Reaction Steps

Under a nitrogen atmosphere 1.50 mL (13.06 mmol) dimethylmalonat, 1.60 g (13.27 mmol) cyclopropanecarboxamidine hydrochloride and 15.0 mL (80.80 mmol) sodium methoxide solution (30%) were refluxed for 1.25 h with stirring. The reaction mixture was slightly acidified and the precipitate formed was suction filtered, washed and dried.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952014B2
Source datasetuspto-grants-2015_02
ORD IDord-d075e8bf99e44000b37766e15f75b103
Source noteuspto-grants-2015_02