反应详情

0.10 g (0.53 mmol) 4,6-dichloro-2-cyclopropylpyrimidine were added to 95 mg (0.55 mmol) 6-hydroxy-4-methylbenzo[d]oxazol-2(3H)-one and 0.21 g (0.63 mmol) caesium carbonate in 1.5 mL DMF after 15 min and the mixture was stirred overnight at RT. The reaction mixture was purified by preparative HPLC-MS. The fractions containing product were combined and freeze-dried.

1. customThe reaction mixture was purified by preparative HPLC-MS
2. additionThe fractions containing product
3. customfreeze-dried