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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846483Generated: November 1, 2026

Water → HCID 86663919, compound

https://huagongshe.com/reaction/1846483

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPotassium CarbonateHCID 11430—
Reactant4,6-DichloropyrimidineHCID 70943—
ReactantHCID 14365009HCID 14365009—
SolventDimethylformamideHCID 6228—
ProductHCID 86663919HCID 86663919—

Reaction Steps

270 mg (1.81 mmol) 4,6-dichloropyrimidine, 330 mg (1.81 mmol) 4-chloro-5-hydroxy-2-methyl-1H-benzo[d]imidazole and 270 mg (1.95 mmol) potassium carbonate in 1.5 mL DMF were stirred for 2 h at RT. The reaction mixture was mixed with water and the precipitate formed was suction filtered, washed and dried.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952014B2
Source datasetuspto-grants-2015_02
ORD IDord-b550eef10a354aa9ad7a9d11ed0adb89
Source noteuspto-grants-2015_02