Hydrochloric Acid → HCID 21820480, compound

Participants

Reaction Steps

A mixture of 1.15 g (3.63 mmol) 5-methyl-4-nitro-1,3-phenylenediacetate and 10.0 mL (10.0 mmol) 1M aqueous lithium hydroxide solution in 10.0 mL methanol was stirred overnight at RT. The reaction mixture was acidified with 4M hydrochloric acid and extracted with dichloromethane. The organic phase was separated off, dried and evaporated down i.vac. The residue was purified by chromatography. The fractions containing product were combined and evaporated down i.vac.

Provenance & Evidence