Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846493Generated: November 2, 2026

Potassium Carbonate → HCID 178478257, compound

https://huagongshe.com/reaction/1846493

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant4,6-DichloropyrimidineHCID 70943—
ReactantHCID 178516181HCID 178516181—
SolventDimethylformamideHCID 6228—
ProductHCID 178478257HCID 178478257—

Reaction Steps

80 mg (0.34 mmol) 7-chloro-2-(tetrahydrofuran-3-yl)-1H-benzo[d]imidazol-5-ol and 51 mg (0.34 mmol) 4,6-dichloropyrimidine were placed in 2.0 mL DMF. 55 mg (0.40 mmol) potassium carbonate were added and the mixture was stirred overnight at RT. The reaction mixture was filtered and purified by chromatography. The fractions containing product were combined and evaporated down i.vac.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952014B2
Source datasetuspto-grants-2015_02
ORD IDord-9ee0f92b5f7a4a21abe5f6306fc8485c
Source noteuspto-grants-2015_02