HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 178478258, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4,6-Dichloropyrimidine | HCID 70943 | — |
| Reactant | HCID 178516182 | HCID 178516182 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178478258 | HCID 178478258 | — |
Reaction Steps
0.10 g (0.40 mmol) 7-chloro-2-(tetrahydro-2H-pyran-4-yl)-1H-benzo[d]imidazol-5-ol and 60 mg (0.40 mmol) 4,6-dichloropyrimidine were placed in 2.0 mL DMF. 61 mg (0.40 mmol) potassium carbonate were added and the mixture was stirred overnight at RT. The reaction mixture was filtered and purified by chromatography. The fractions containing product were combined and evaporated down i.vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952014B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-b7b1107088c24a0eb6095b61c07fe312 |
| Source note | uspto-grants-2015_02 |