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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846497Generated: November 1, 2026

Potassium Carbonate → HCID 178478258, compound

https://huagongshe.com/reaction/1846497

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant4,6-DichloropyrimidineHCID 70943—
ReactantHCID 178516182HCID 178516182—
SolventDimethylformamideHCID 6228—
ProductHCID 178478258HCID 178478258—

Reaction Steps

0.10 g (0.40 mmol) 7-chloro-2-(tetrahydro-2H-pyran-4-yl)-1H-benzo[d]imidazol-5-ol and 60 mg (0.40 mmol) 4,6-dichloropyrimidine were placed in 2.0 mL DMF. 61 mg (0.40 mmol) potassium carbonate were added and the mixture was stirred overnight at RT. The reaction mixture was filtered and purified by chromatography. The fractions containing product were combined and evaporated down i.vac.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952014B2
Source datasetuspto-grants-2015_02
ORD IDord-b7b1107088c24a0eb6095b61c07fe312
Source noteuspto-grants-2015_02