HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846529Generated: November 1, 2026
Potassium Carbonate → HCID 46244317, compound
https://huagongshe.com/reaction/1846529
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 7-methoxy-3-(piperidin-4-yl)-4,5-dihydro-1H-benzo[d][1,3]diazepin-2(3H)-one | HCID 18356852 | — |
| Reactant | HCID 86663901 | HCID 86663901 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 46244317 | HCID 46244317 | — |
Reaction Steps
59 mg (0.21 mmol) 7-methoxy-3-piperidin-4-yl-1,3,4,5-tetrahydro-1,3-benzodiazepin-2-one, 65 mg (0.19 mmol) N-(6-chloro-pyrimidin-4-yl)-N-(3,4-dimethyl-2-oxo-2,3-dihydro-benzoxazol-6-yl)-acetamide and 81 mg (0.59 mmol) potassium carbonate in 1.5 mL NMP were combined and stirred at 80° C. The reaction mixture was purified by preparative HPLC. The product-containing fractions were combined and evaporated down. The solid obtained was washed with diethyl ether and dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08952014B2 |
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| Source dataset | uspto-grants-2015_02 |
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| ORD ID | ord-d96357fa18f04c459a45823163da28f5 |
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| Source note | uspto-grants-2015_02 |
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