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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846581Generated: November 2, 2026

Diisopropylethylamine → HCID 46243985, compound

https://huagongshe.com/reaction/1846581

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantSpiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-oneHCID 56651734—
ReactantHCID 86663906HCID 86663906—
SolventDimethylformamideHCID 6228—
ProductHCID 46243985HCID 46243985—

Reaction Steps

36 mg (0.15 mmol) spiro[piperidin-4.3′-pyrrolo[2,3-b]pyridin]-2′(1′H)-one, 44 mg (0.15 mmol) 6-(6-chloro-2-methylpyrimidin-4-yloxy)-4-methylbenzo[d]oxazol-2(3H)-one and 91 μL (0.536 mmol) DIPEA in 2.0 mL DMF were stirred for 48 h at RT. The reaction mixture was purified by preparative HPLC-MS. The fractions containing product were combined and lyophilised.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952014B2
Source datasetuspto-grants-2015_02
ORD IDord-0c60120c021d43eda2ee8c1fbc984cad
Source noteuspto-grants-2015_02