反应详情

36 mg (0.15 mmol) spiro[piperidin-4.3′-pyrrolo[2,3-b]pyridin]-2′(1′H)-one, 44 mg (0.15 mmol) 6-(6-chloro-2-methylpyrimidin-4-yloxy)-4-methylbenzo[d]oxazol-2(3H)-one and 91 μL (0.536 mmol) DIPEA in 2.0 mL DMF were stirred for 48 h at RT. The reaction mixture was purified by preparative HPLC-MS. The fractions containing product were combined and lyophilised.

1. customThe reaction mixture was purified by preparative HPLC-MS
2. additionThe fractions containing product