HCID 71238060, compound → HCID 68304200, compound

Participants

Reaction Steps

A mixture of 0.090 g (0.24 mmol) of (6′-methanesulfonyl-3′-nitro-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl)-acetic acid ethyl ester and 0.015 g (0.014 mmol) of 10% palladium on carbon in ethanol (8 mL) is stirred overnight under an atmosphere of hydrogen. The mixture is passed through a pad of diatomaceous earth and concentrated under reduced pressure to provide 0.076 g (94%) of (3′-amino-6′-methanesulfonyl-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-4-yl)-acetic acid ethyl ester as a black oil.

Provenance & Evidence