1-(3-Aminophenyl)pyrrolidin-2-one → HCID 46184366, compound

HRID 1846720Notes

Reaction equation

HRID 1846720 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19](C3ON=CC=3)=[CH:18][CH:17]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1.NC1C=C([N:37]2[CH2:41][CH2:40][CH2:39][C:38]2=[O:42])C=CC=1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([N:37]3[CH2:41][CH2:40][CH2:39][C:38]3=[O:42])[CH:17]=2)[C:12]([C:27]([NH2:29])=[O:28])=[CH:11][N:10]=1

Participants

3

Reactant 2

HCID 6839561-(3-Aminophenyl)pyrrolidin-2-oneHCID 461846122-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamide

Product 1

HCID 46184366HCID 46184366, compound

Procedure

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 1-(3-aminophenyl)pyrrolidin-2-one in step 1. MS: 410.5 (M+H).

Workup

  1. customThis compound was synthesised

Sources & evidence

ORD record
ord-bb397d5c3bef4720b8134c6ad38de29c
Source dataset
uspto-grants-2015_02
Patent number
US08952027B2

Reaction notes

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