HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylbenzenesulphonyl chloride → N-(5-Benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-3-methyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylbenzenesulphonyl chloride | HCID 2734595 | — |
| Reactant | 2-Aminomethyl-5-benzyloxy-pyran-4-one | HCID 21524753 | — |
| Reactant | N-(5-benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-benzene sulfonamide | HCID 86725690 | — |
| Product | N-(5-Benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-3-methyl-benzenesulfonamide | HCID 86725714 | 57.6% |
Reaction Steps
N-(5-Benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-3-methyl-benzenesulfonamide (7-04) (24.0 g, 57.60%) was synthesized as a light brown solid from 2-aminomethyl-5-benzyloxy-pyran-4-one (5) and 3-methyl-benzenesulfonyl chloride (6-04) (24.67 g, 129.87 mmol) following the procedure described for N-(5-benzyloxy-4-oxo-4H-pyran-2-ylmethyl)-benzenesulfonamide (7-01).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08952039B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-8488af88c4464a95b229f66409881e03 |
| Source note | uspto-grants-2015_02 |