反应详情

Benzyl 4-(3,3-dimethoxypropyl)-6-methoxy-3-oxo-3,4-dihydroquinoxalin-1(2H)-carboxylate (386 mg, 0.931 mmol) was dissolved in methanol (5 ml), 10% palladium on carbon (50% wet, 200 mg) was added thereto and the mixture was stirred at room temperature for 4 hours under a hydrogen gas atmosphere. After removing the catalyst by filtration using celite, the filtrate was concentrated under reduced pressure to yield 201 mg (77%) of a crude product of the title compound in the form of a yellow oil.

1. customAfter removing the catalyst
2. filtrationby filtration
3. concentrationthe filtrate was concentrated under reduced pressure