反应详情

Ergosterol (35.7 g, 90.0 mmol) was dissolved in dimethoxymethane (350 mL, 6.3 mol), and diphosphorous pentoxide (17.9 g, 126 mmol) was added thereto, followed by stirring at room temperature for 1 hour. Diatomaceous earth was added to the reaction mixture, followed by stirring for 30 minutes and filtration, and the filtrate was concentrated. Ethyl acetate was added to the resulting residue for trituration to obtain the title compound (35.1 g, 89%).

1. additionDiatomaceous earth was added to the reaction mixture
2. stirringby stirring for 30 minutes
3. filtrationfiltration
4. concentrationthe filtrate was concentrated
5. additionEthyl acetate was added to the resulting residue for trituration