(4-Methoxyphenyl)boronic acid → HCID 136344053, compound

HRID 1847220Notes

Reaction equation

HRID 1847220 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:22])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10](Br)[N:11]=1)=[O:5])[CH3:2].[CH3:23][O:24][C:25]1[CH:30]=[CH:29][C:28](B(O)O)=[CH:27][CH:26]=1>>[CH2:1]([O:3][C:4]([C:6]1[C:7]([OH:22])=[C:8]2[C:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[N:14][S:13][C:9]2=[C:10]([C:28]2[CH:29]=[CH:30][C:25]([O:24][CH3:23])=[CH:26][CH:27]=2)[N:11]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 136344015HCID 136344015, compound

Product 1

HCID 136344053HCID 136344053, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 7-bromo-4-hydroxy-3-phenyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid ethyl ester and 4-methoxyphenylboronic acid: MS (m/z) 407.2 (M+1).

Sources & evidence

ORD record
ord-f69d05d8d2754d68a3e7abda83724f92
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

Loading…