Phenylboronic Acid → HCID 136344025, compound

HRID 1847260Notes

Reaction equation

HRID 1847260 reaction equation
[CH2:1]([O:5][C:6]([C:8]1[C:9]([OH:19])=[C:10]2[C:17]([CH3:18])=[N:16][S:15][C:11]2=[C:12](Br)[N:13]=1)=[O:7])[CH2:2][CH2:3][CH3:4].[C:20]1(B(O)O)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:1]([O:5][C:6]([C:8]1[C:9]([OH:19])=[C:10]2[C:17]([CH3:18])=[N:16][S:15][C:11]2=[C:12]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[N:13]=1)=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 136343979HCID 136343979, compound

Product 1

HCID 136344025HCID 136344025, compound

Procedure

The title compound was synthesized in analogy to Example 1 from 7-Bromo-4-hydroxy-3-methyl-isothiazolo[5,4-c]pyridine-5-carboxylic acid butyl ester and phenyl boronic acid: MS (m/z) 343.1 (M+1).

Sources & evidence

ORD record
ord-d82d5c172ad041a7bb0624b3ef52f9cb
Source dataset
uspto-grants-2015_02
Patent number
US08952160B2

Reaction notes

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