Potassium Cation → 7-(2-Aminopyrimidin-5-yl)-1-[(dicyclopropylmethyl)amino]-5H-pyrido[4,3-b]indole-4-carboxamide
Reaction equation
[CH3:26][C:27]1([CH3:28])[C:29]([CH3:30])([CH3:31])[O:32][B:33]([c:34]2[cH:35][n:36][c:37]([NH2:40])[n:38][cH:39]2)[O:41]1.[CH:42]1([P:43]([CH:44]2[CH2:45][CH2:46][CH2:47][CH2:48][CH2:49]2)[CH:50]2[CH2:51][CH2:52][CH2:53][CH2:54][CH2:55]2)[CH2:56][CH2:57][CH2:58][CH2:59][CH2:60]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]3[c:7]([nH:8][c:9]2[cH:10]1)[c:11]([C:23](=[O:24])[NH2:25])[cH:12][n:13][c:14]3[NH:15][CH:16]([CH:17]1[CH2:18][CH2:19]1)[CH:20]1[CH2:21][CH2:22]1.[K+:66].[K+:67].[K+:68].[O:113]=[C:114]([CH:115]=[CH:116][c:117]1[cH:118][cH:119][cH:120][cH:121][cH:122]1)[CH:123]=[CH:124][c:125]1[cH:126][cH:127][cH:128][cH:129][cH:130]1.[O:69]1[CH2:70][CH2:71][O:72][CH2:73][CH2:74]1.[O:77]=[C:78]([CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1)[CH:87]=[CH:88][c:89]1[cH:90][cH:91][cH:92][cH:93][cH:94]1.[O:95]=[C:96]([CH:97]=[CH:98][c:99]1[cH:100][cH:101][cH:102][cH:103][cH:104]1)[CH:105]=[CH:106][c:107]1[cH:108][cH:109][cH:110][cH:111][cH:112]1.[P:61]([O-:62])([O-:63])([O-:64])=[O:65].[Pd:75].[Pd:76]>>[c:2]1(-[c:34]2[cH:35][n:36][c:37]([NH2:40])[n:38][cH:39]2)[cH:3][cH:4][c:5]2[c:6]3[c:7]([nH:8][c:9]2[cH:10]1)[c:11]([C:23](=[O:24])[NH2:25])[cH:12][n:13][c:14]3[NH:15][CH:16]([CH:17]1[CH2:18][CH2:19]1)[CH:20]1[CH2:21][CH2:22]1Participants
9
Reactant 8
HCID 813Potassium Cation3×
HCID 1061Phosphate
HCID 23938Palladium2×
HCID 312751,4-Dioxane
HCID 75806Tricyclohexylphosphine
HCID 95417Dibenzylidene acetone3×
HCID 177502122-Aminopyrimidine-5-boronic acid, pinacol ester
HCID 565953257-Chloro-1-[(dicyclopropylmethyl)amino]-5H-pyrido[4,3-b]indole-4-carboxamideProduct 1
Sources & evidence
- ORD record
- ord-c915f7ad9ab74166bc21946a45dd8dae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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