Methanol → Pictilisib

HRID 184837Notes

Reaction equation

HRID 184837 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][N:8]([CH2:11][c:12]2[cH:13][c:14]3[n:15][c:16](-[c:27]4[c:28]5[cH:29][n:30]([CH:36]6[CH2:37][CH2:38][CH2:39][CH2:40][O:41]6)[n:31][c:32]5[cH:33][cH:34][cH:35]4)[n:17][c:18]([N:21]4[CH2:22][CH2:23][O:24][CH2:25][CH2:26]4)[c:19]3[s:20]2)[CH2:9][CH2:10]1.[CH3:42][OH:43].[CH3:44][S:45](=[O:46])(=[O:47])[OH:48].[OH2:49]>>[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][N:8]([CH2:11][c:12]2[cH:13][c:14]3[n:15][c:16](-[c:27]4[c:28]5[cH:29][n:30][nH:31][c:32]5[cH:33][cH:34][cH:35]4)[n:17][c:18]([N:21]4[CH2:22][CH2:23][O:24][CH2:25][CH2:26]4)[c:19]3[s:20]2)[CH2:9][CH2:10]1

Participants

5

Reactant 4

HCID 887MethanolHCID 962WaterHCID 6395Methanesulfonic AcidHCID 25268845HCID 25268845, compound

Product 1

HCID 17755052Pictilisib

Sources & evidence

ORD record
ord-e9b1e35babc9478bae0f375daa09b378
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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