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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1848495Generated: October 31, 2026

3-Methyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one → 3-Ethyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/1848495

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-oneHCID 86709458—
ReactantTert-butyl 3-ethyl-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylateHCID 86709505—
Product3-Ethyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-oneHCID 86709506—

Reaction Steps

The title compound was prepared in two steps from tert-butyl 3-ethyl-1-oxo-2,8-diazaspiro[4.5]decane-8-carboxylate in an analogous fashion as described for 3-methyl-2-(5-oxo-2,5-dihydrofuran-3-yl)-2,8-diazaspiro[4.5]decan-1-one (I-22).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952166B2
Source datasetuspto-grants-2015_02
ORD IDord-27556186f0fa4ad5bc7e62e4113026a4
Source noteuspto-grants-2015_02