HCID 86673667, compound → HCID 86673671, compound

HRID 1848674Notes

Reaction equation

HRID 1848674 reaction equation
[C:1]([O:7][CH2:8][CH:9]([O:16][C:17](=[O:22])[CH2:18][CH2:19][CH2:20][CH3:21])[C:10](=[N+]=[N-])[C:11](=[O:13])[CH3:12])(=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5].CC(C)=[O:25].CC1(C)OO1>CC(C)=O>[C:1]([O:7][CH2:8][CH:9]([O:16][C:17](=[O:22])[CH2:18][CH2:19][CH2:20][CH3:21])[C:10](=[O:25])[C:11](=[O:13])[CH3:12])(=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 86673667HCID 86673667, compoundHCID 86673672HCID 86673672, compound

Product 1

HCID 86673671HCID 86673671, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of methyl diazo dipentanoate 9 (27 mg, 0.086 mmol) in acetone (1 mL) was added dimethyldioxirane acetone solution (2.5 mL, ca. 0.07-0.09 M). The resulting mixture was stirred for 1 h and solvent and excess reagents were removed under reduced pressure to obtain 21 as bright yellow oil (yield=26 mg, quantitative).

Workup

  1. customsolvent and excess reagents were removed under reduced pressure

Sources & evidence

ORD record
ord-56d96e712e7046cbbe86f2a160b3fe9d
Source dataset
uspto-grants-2015_02
Patent number
US08952192B2

Reaction notes

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