Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Benzonitrile | HCID 7505 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Product | HCID 178513316 | HCID 178513316 | — |
Reaction Steps
To a solution of the benzonitrile intermediate in methanol was added hydroxylamine hydrochloride. After heating to 50° C. with stirring for 16 h, the reaction mixture was cooled to RT and concentrated to afford the corresponding N-hydroxy-4-(hydroxymethyl)benz-imidamide derivative.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08957051B2 |
|---|
| Source dataset | uspto-grants-2015_02 |
|---|
| ORD ID | ord-8ff974435db34826b6ee389080fb1a2c |
|---|
| Source note | uspto-grants-2015_02 |
|---|
