反应详情

To a solution of (S)-tert-butyl (1-(5-phenyl-1,3,4-thiadiazol-2-yl)ethyl)carbamate (110 mg, 0.4 mmol, in 5 ml of DCM) was added 1 ml of TFA, the reaction mixture was stirred at room temperature for 3 hours, the solvent was removed to yield the desired product (52 mg) in 66.8% yield. LCMS m/z 206.0 (M+H)+ RT=0.97 min.

1. customthe solvent was removed