Hydrochloric Acid → HCID 67997439, compound

Participants

Reaction Steps

To a solution of 4 N HCl in MeOH (10 mL) was added (21) (120 mg, 0.35 mmol) at 0° C. and the resulting mixture was stirred at RT for 1 h. The mixture was concentrated under reduced pressure to give 2-azetidin-3-yl-3-(4-methoxy-phenyl)-pyrazine (22) (95 mg, yield 100%) which was used for the next step without further purification. ESI-MS (M+1): 242 calc. for C14H15N3O 241.

Provenance & Evidence