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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1850297Generated: November 1, 2026

Hydrochloride methanol → HCID 86660167, compound

https://huagongshe.com/reaction/1850297

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloride methanolHCID 21893726—
ReactantHCID 58546744HCID 58546744—
ProductHCID 86660167HCID 86660167100%

Reaction Steps

A mixture of 3-(3-phenyl-pyridin-2-yl)-azetidine-1-carboxylic acid tert-butyl ester (99) (216 mg, 0.60 mmol) in 4 M HCl/MeOH solution (10 mL) was stirred at RT. for 30 min. Then the solvent was evaporated at 40° C. to give 2-azetidin-3-yl-3-phenyl-pyridine (100) (177 mg, 100% yield) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957073B2
Source datasetuspto-grants-2015_02
ORD IDord-2bca621cec9445019b9b92485849e456
Source noteuspto-grants-2015_02