HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58547508, compound → HCID 58547425, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58547508 | HCID 58547508 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 58547425 | HCID 58547425 | 57.1% |
Reaction Steps
To a solution of (1H-Benzoimidazol-2-yl)-[3-(2-chloro-5-phenyl-pyrimidin-4-yl)-azetidin-1-yl]-methanone (102 mg, 0.28 mmol) in MeOH (10 mL) was added Pd/C (100 mg). The reaction solution was stirred at RT overnight under H2 atmosphere. The mixture was filtered and concentrated to give the product (51 mg, 0.16 mmol, yield: 55%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957073B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c8f932d3b1ab4d53a652c3e7509f12a0 |
| Source note | uspto-grants-2015_02 |