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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1850340Generated: October 29, 2026

HCID 58547508, compound → HCID 58547425, compound

https://huagongshe.com/reaction/1850340

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58547508HCID 58547508—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 58547425HCID 5854742557.1%

Reaction Steps

To a solution of (1H-Benzoimidazol-2-yl)-[3-(2-chloro-5-phenyl-pyrimidin-4-yl)-azetidin-1-yl]-methanone (102 mg, 0.28 mmol) in MeOH (10 mL) was added Pd/C (100 mg). The reaction solution was stirred at RT overnight under H2 atmosphere. The mixture was filtered and concentrated to give the product (51 mg, 0.16 mmol, yield: 55%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08957073B2
Source datasetuspto-grants-2015_02
ORD IDord-c8f932d3b1ab4d53a652c3e7509f12a0
Source noteuspto-grants-2015_02