Dichloromethane → 7-(3-Bromopropoxy)-6-methoxy-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-4-one
Reaction equation
[Br:35][CH2:36][CH2:37][CH2:38][OH:39].[CH2:59]([Cl:60])[Cl:61].[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[OH:13][c:14]1[c:15]([O:33][CH3:34])[cH:16][c:17]2[c:18](=[O:32])[n:19]([CH2:24][O:25][C:26]([C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:20][n:21][c:22]2[cH:23]1.[c:40]1([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[cH:54][cH:55][cH:56][cH:57][cH:58]1>>[O:13]([c:14]1[c:15]([O:33][CH3:34])[cH:16][c:17]2[c:18](=[O:32])[n:19]([CH2:24][O:25][C:26]([C:27]([CH3:28])([CH3:29])[CH3:30])=[O:31])[cH:20][n:21][c:22]2[cH:23]1)[CH2:38][CH2:37][CH2:36][Br:35]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ef8b0c0a02304206b39f34000178d9cb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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