Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 5-Chloro-7-(4-dimethylamino-3-methylphenyl)-[1,6]naphthyridine | HCID 44632882 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 58483120 | HCID 58483120 | — |
Reaction Steps
100 mg (0.31 mmol) of 6.1 was placed in 0.5 ml dimethylacetamide and then 60 mg (1.1 mmol) sodium methoxide were added. The reaction mixture was stirred for 1 h at 50° C. The mixture was purified by chromatography (RP-HPLC-MS), the corresponding fractions were freeze-dried.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08957088B2 |
|---|
| Source dataset | uspto-grants-2015_02 |
|---|
| ORD ID | ord-9fd2f608e47c4136bef18f3794eba00f |
|---|
| Source note | uspto-grants-2015_02 |
|---|
