反应详情

2-({1-[1-(4-Chlorophenyl)cyclobutyl]-4,4-dimethyl-3,4-dihydroisoquinolin-7-yl}oxy)ethanamine was prepared analogously to 2-({1-[1-(4-fluorophenyl)cyclobutyl]-3,4-dihydroisoquinolin-7-yl}oxy)ethanamine (cf. example 65) using 2-(4-methoxyphenyl)-2-methylpropan-1-amine and 1-(4-chlorophenyl)cyclobutanecarboxylic acid in place of 2-(4-methoxyphenyl)ethanamine and 1-(4-fluorophenyl)cyclobutanecarboxylic acid, respectively.