反应详情

100 mg 4-(6-phenyl-3-vinylimidazo[1,2-a]pyrimidin-7-yl)benzaldehyde (prepared as described under intermediate example 13) were dissolved in a mixture of 5 mL THF and 5 mL EtOH. 10 mg 10% Pd/C were added and the mixture stirred under an atmosphere of hydrogen for 2 h. The mixture was filtered through Celite, the solvent was evaporated and the crude product was purified by chromatography on silica gel (dichloromethane/methanol).

1. filtrationThe mixture was filtered through Celite
2. customthe solvent was evaporated
3. customthe crude product was purified by chromatography on silica gel (dichloromethane/methanol)