HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-pyridine → HCID 178498894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-pyridine | HCID 68752284 | — |
| Reactant | 6-(2,6-Difluorophenyl)-5-(4-formylphenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid methyl ester | HCID 86703046 | — |
| Product | HCID 178498894 | HCID 178498894 | — |
Reaction Steps
The compound is prepared in analogy to example 27.0. 348.5 mg 2-(5-Azetidine-3-yl-[1,2,4]triazole-3-yl)-pyridine×2HCl are reacted with 500 mg (1.27 mmol) 6-(2,6-difluorophenyl)-5-(4-formylphenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid methyl ester. After the usual work-up and purification 254 mg (32.9%) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08957064B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-da56e30bf2c4498491771a92f0b53733 |
| Source note | uspto-grants-2015_02 |