反应详情

温度

50 °C

A mixture of 7-nitro-1H-indole-2-carboxamide (2.50 g), Lawesson's reagent (5.42 g) and tetrahydrofuran (50 mL) was stirred at 50° C. overnight. The reaction mixture was concentrated, and the resulting crystals were filtrated, washed with toluene, and dried to give the title compound (2.08 g, yield 77%) as yellow crystals. melting point>237° C. (decomposition).

1. concentrationThe reaction mixture was concentrated
2. filtrationthe resulting crystals were filtrated
3. washwashed with toluene
4. customdried