Potassium Cation → 2-Amino-4-(2,4-dichloro-5-(2,2-diethoxyethoxy)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl amide

HRID 185165Notes

Reaction equation

HRID 185165 reaction equation
[CH2:32]([CH3:33])[O:34][CH:35]([CH2:36][Br:37])[O:38][CH2:39][CH3:40].[CH2:7]([CH3:8])[NH:9][C:10](=[O:11])[c:12]1[cH:13][c:14]2[c:15]([n:16][c:17]([NH2:29])[n:18][c:19]2-[c:20]2[c:21]([Cl:28])[cH:22][c:23]([Cl:27])[c:24]([OH:26])[cH:25]2)[s:30]1.[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH3:41][C:42]#[N:43].[K+:6].[OH2:31]>>[CH2:7]([CH3:8])[NH:9][C:10](=[O:11])[c:12]1[cH:13][c:14]2[c:15]([n:16][c:17]([NH2:29])[n:18][c:19]2-[c:20]2[c:21]([Cl:28])[cH:22][c:23]([Cl:27])[c:24]([O:26][CH2:36][CH:35]([O:34][CH2:32][CH3:33])[O:38][CH2:39][CH3:40])[cH:25]2)[s:30]1

Participants

7

Reactant 6

HCID 813Potassium CationHCID 962WaterHCID 6342AcetonitrileHCID 74852Ethane, 2-bromo-1,1-diethoxy-HCID 45749132-Methylpropan-2-olateHCID 442202982-Amino-4-(2,4-dichloro-5-hydroxyphenyl)-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl amide

Product 1

HCID 442209122-Amino-4-(2,4-dichloro-5-(2,2-diethoxyethoxy)-phenyl)-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl amide

Sources & evidence

ORD record
ord-1e9aa5a6f67249569ff1964d6defa4f8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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