Trifluoroacetic acid → HCID 68313806, compound

HRID 1851672Notes

Reaction equation

HRID 1851672 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[NH:21][N:22]=[CH:23][CH:24]=3)=[CH:16][N:15]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[F:25][C:26]([F:31])([F:30])[C:27]([OH:29])=[O:28]>>[F:25][C:26]([F:31])([F:30])[C:27]([OH:29])=[O:28].[N:22]1[NH:21][C:20]([C:17]2[CH:18]=[CH:19][C:14]([N:11]3[CH2:12][CH2:13][NH:8][CH2:9][CH2:10]3)=[N:15][CH:16]=2)=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 68313933HCID 68313933, compound

Product 1

HCID 68313806HCID 68313806, compound

Procedure

The compound of step b) (0.11 g) is dissolved slowly in 3.5 ml of trifluoroacetic acid at 0° C. The resulting product is then left to stir for 2 hours at ambient temperature. The trifluoroacetic acid is evaporated off under vacuum and 0.065 g of the title compound is obtained in the form of a white solid.

Workup

  1. waitThe resulting product is then left
  2. customThe trifluoroacetic acid is evaporated off under vacuum

Sources & evidence

ORD record
ord-edbc52b1a8be4614a5f2ed6ccd9c6c00
Source dataset
uspto-grants-2015_02
Patent number
US08957211B2

Reaction notes

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