Cyclobutylamine → HCID 71074846, compound

HRID 1851912Notes

Reaction equation

HRID 1851912 reaction equation
[CH:1]1([NH2:5])[CH2:4][CH2:3][CH2:2]1.C([O:10][C:11]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[C:19]1[CH:24]=[CH:23][C:22]([CH2:25][N:26]2[C:34]3[C:29](=[CH:30][C:31]([C:35](O)=[O:36])=[CH:32][CH:33]=3)[C:28]([CH3:38])=[C:27]2[CH3:39])=[CH:21][CH:20]=1)=[O:12])(C)(C)C>>[CH:1]1([NH:5][C:35]([C:31]2[CH:30]=[C:29]3[C:34](=[CH:33][CH:32]=2)[N:26]([CH2:25][C:22]2[CH:21]=[CH:20][C:19]([C:14]4[C:13]([C:11]([OH:12])=[O:10])=[CH:18][CH:17]=[CH:16][CH:15]=4)=[CH:24][CH:23]=2)[C:27]([CH3:39])=[C:28]3[CH3:38])=[O:36])[CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 75645CyclobutylamineHCID 710746641-((2'-(tert-Butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid

Product 1

HCID 71074846HCID 71074846, compound

Procedure

The title compound was prepared following the same general protocol as described in Steps 8-9, Example 1, using cyclobutylamine and 1-((2′-(tert-butoxycarbonyl)biphenyl-4-yl)methyl)-2,3-dimethyl-1H-indole-5-carboxylic acid.

Sources & evidence

ORD record
ord-d0ba5703b1d24851a80696d4d25366f8
Source dataset
uspto-grants-2015_02
Patent number
US08957093B2

Reaction notes

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