Sodium Hydroxide → potassium sodium D-glucarate

Participants

Reaction Steps

Aqueous sodium hydroxide solution (33 mL, 6 M) was added to a slurry of monopotassium D-glucarate (50.0 g. 0.201 mol) in water (150 mL) until all of the solid dissolved and a constant pH of 9.7 was reached. The solution was concentrated to a syrup and seeded with the title compound. A solid crystalline cake formed over 24 h. The crystals were isolated by filtration, washed with cold 1:1 ethanol/water (3×15 mL), and dried under reduced pressure to give sodium potassium D-glucarate as colorless crystals (48.2 g, 0.157 mol as the dihydrate, 78.3%).

Provenance & Evidence