Potassium Hydroxide → Dipotassium D-glucarate

HRID 1852318Notes

Reaction equation

HRID 1852318 reaction equation
[OH-].[K+:2].[O:3]=[C:4]([OH:16])[C@@H:5]([C@H:7]([C@@H:9]([C@@H:11]([C:13]([O-:15])=[O:14])[OH:12])[OH:10])[OH:8])[OH:6].[K+]>O>[O:3]=[C:4]([O-:16])[C@@H:5]([C@H:7]([C@@H:9]([C@@H:11]([C:13]([O-:15])=[O:14])[OH:12])[OH:10])[OH:8])[OH:6].[K+:2].[K+:2]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 86593939Potassium hydrogen saccharate

Product 1

HCID 23624071Dipotassium D-glucarate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Aqueous potassium hydroxide solution (27 mL, 2 M) was added to a slurry of monopotassium D-glucarate (10.2 g, 41.1 mmol) in water (50 mL) until all of the solid dissolved and a constant pH of 10 was reached. The solution was concentrated to a syrup and seeded with the title compound. Crystals grew slowly from the syrup. After two weeks, the crystals were isolated by filtration, washed with cold 1:1 ethanol/water (3×5 mL), and dried under reduced pressure to give dipotassium D-glucarate as colorless crystals (8.14 g, 26.8 mmol as the monohydrate, 65.1%).

Workup

  1. dissolutiondissolved
  2. concentrationThe solution was concentrated to a syrup
  3. waitAfter two weeks
  4. customthe crystals were isolated by filtration
  5. washwashed with cold 1:1 ethanol/water (3×5 mL)
  6. customdried under reduced pressure

Sources & evidence

ORD record
ord-67ffbf72ad764d2fbee7eb89bd377eb0
Source dataset
uspto-grants-2015_02
Patent number
US08961813B2

Reaction notes

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