Potassium Hydroxide → Dipotassium D-glucarate

Participants

Reaction Steps

Aqueous potassium hydroxide solution (27 mL, 2 M) was added to a slurry of monopotassium D-glucarate (10.2 g, 41.1 mmol) in water (50 mL) until all of the solid dissolved and a constant pH of 10 was reached. The solution was concentrated to a syrup and seeded with the title compound. Crystals grew slowly from the syrup. After two weeks, the crystals were isolated by filtration, washed with cold 1:1 ethanol/water (3×5 mL), and dried under reduced pressure to give dipotassium D-glucarate as colorless crystals (8.14 g, 26.8 mmol as the monohydrate, 65.1%).

Provenance & Evidence