HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → 5-methoxycarbonylpentyl alpha-D-mannopyranoside
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 5-ethoxycarbonylpentyl 2,3,4,6-tetra-O-acetyl-alpha-D-mannopyranoside | HCID 12151683 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-methoxycarbonylpentyl alpha-D-mannopyranoside | HCID 66848124 | 100% |
Reaction Steps
To compound 1 (3.7 g, 7.55 mmol) dissolved in 35 mL of anhydrous methanol, sodium methylate (1.6 g, 30.20 mmol) was added. After 30 min under stirring, cation exchange resin (Dowex® 50WX2, H+ form, 13 g) was added. After 1 h the resin was filtered and washed with methanol. The filtrate was concentrated under reduced pressure yielding 2 (2.1 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962573B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-de1454e25e2641c98b1d968df69a96f9 |
| Source note | uspto-grants-2015_02 |