Water → HCID 178508285, compound

Participants

Reaction Steps

1.87 g (10.7 mmol) benzamidin hydrochloride hydrate and 0.89 g (10.7 mmol) sodium acetate are added to 1.0 g (3.6 mmol) 5-amino-4-cyano-3-(4-bromophenyl)aminopyrazol in 20 ml ethanoic acid by stirring. The reaction mixture is boiled for a period of 4 h, treated with 50 ml water, filtered and washed with 20 ml of cold methanol and 20 ml of cold ester. The raw product is purified by means of crystallization from ethanol.

Provenance & Evidence