O-tert-butylhydroxylamine hydrochloride → HCID 86673027, compound

Participants

Reaction Steps

6-bromo-2-isoquinolin-3-yl-chromen-4-one O-tert-butyl oxime was prepared using the method D (step 1) illustrated in example 1B. 6-bromo-2-isoquinolin-3-yl-chromen-4-one (600 mg, 1.7 mmol) was treated with O-tert-butyl-hydroxylamine hydrochloride (427 mg, 3.4 mmol) in methanol (10 ml) under microwave irradiation to yield 6-bromo-2-isoquinolin-3-yl-chromen-4-one O-tert-butyl oxime (546 mg, 76%) as a yellow solid.

Provenance & Evidence