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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1853327Generated: November 1, 2026

4-(Trifluoromethyl)piperidine → HCID 131732484, compound

https://huagongshe.com/reaction/1853327

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)piperidineHCID 136469—
Reactant6-(2-chloro-ethoxy)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl oximeHCID 86673076—
ProductHCID 131732484HCID 131732484—

Reaction Steps

2-pyrrolo[1,2-c]pyrimidin-3-yl-6-[2-(4-trifluoromethyl-piperidin-1-yl)-ethoxy]chromen-4-one oxime, hydrochloride was prepared in 34% overall yield using the method described in example 87, starting from 6-(2-chloro-ethoxy)-2-pyrrolo[1,2-c]pyrimidin-3-yl-chromen-4-one O-tert-butyl oxime (example 87B) and 4-trifluoromethyl-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08962627B2
Source datasetuspto-grants-2015_02
ORD IDord-22b86c982436425da3103eb8d3fdc102
Source noteuspto-grants-2015_02