HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-chloroethyl)-1H-imidazole hydrochloride → 6-(2-Imidazol-1-yl-ethoxy)-2-pyrrolo[1,2-a]pyrazin-3-yl-chromen-4-one oxime, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-chloroethyl)-1H-imidazole hydrochloride | HCID 2757503 | — |
| Reactant | 6-Hydroxy-2-pyrrolo[1,2-a]pyrazin-3-yl-chromen-4-one O-tert-butyl-oxime | HCID 86673097 | — |
| Product | 6-(2-Imidazol-1-yl-ethoxy)-2-pyrrolo[1,2-a]pyrazin-3-yl-chromen-4-one oxime, hydrochloride | HCID 131732491 | — |
Reaction Steps
6-(2-Imidazol-1-yl-ethoxy)-2-pyrrolo[1,2-a]pyrazin-3-yl-chromen-4-one oxime, hydrochloride was prepared in 13% overall yield using the method described in example 123, starting from 6-Hydroxy-2-pyrrolo[1,2-a]pyrazin-3-yl-chromen-4-one O-tert-butyl-oxime (example 123B) and 1-(2-Chloro-ethyl)-1H-imidazole hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962627B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-1dc26d65eb6f4e5bbdad6748a3454b6f |
| Source note | uspto-grants-2015_02 |