HRID1853347

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67197404

未命名化合物

结构：CC(C)(C)ON=c1cc(-c2cc3sccc3cn2)oc2ccc(O)cc12

HCID86673101

未命名化合物

PRODUCTS

生成物

结构：Cl.ON=c1cc(-c2cc3sccc3cn2)oc2ccc(OCCN3CCC(F)(F)C3)cc12

HCID137187586

未命名化合物

PROCEDURE

实验过程

6-[2-(3,3-Difluoro-pyrrolidin-1-yl)-ethoxy]-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one oxime, hydrochloride was prepared in 62% overall yield using the method described in example 127, starting from 6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime (example 127B) and 1-(2-Chloro-ethyl)-3,3-difluoro-pyrrolidine hydrochloride (WO2008/86404).

WORKUP

后处理

customoverall yield