HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime → 6-(1-Pyrimidin-2-yl-piperidin-4-yloxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime | HCID 86673101 | — |
| Reactant | Methanesulfonic acid 1-pyrimidin-2-yl-piperidin-4-yl ester | HCID 86673125 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 6-(1-Pyrimidin-2-yl-piperidin-4-yloxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime | HCID 86673124 | — |
Reaction Steps
6-(1-Pyrimidin-2-yl-piperidin-4-yloxy)-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime was prepared using the procedure described in example 85A, starting from 6-Hydroxy-2-thieno[3,2-c]pyridin-6-yl-chromen-4-one O-tert-butyl-oxime (example 127B) and methanesulfonic acid 1-pyrimidin-2-yl-piperidin-4-yl ester (example 169B) in dimethylformamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962627B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-b10a5b5de8a049dab3110bea34256923 |
| Source note | uspto-grants-2015_02 |