HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 18534Generated: October 25, 2026
Water → 1-(4-Nitrophenyl)pyrimidine-2,4-dione
https://huagongshe.com/reaction/18534
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Uracil | HCID 1174 | — |
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 1-(4-Nitrophenyl)pyrimidine-2,4-dione | HCID 11276338 | — |
Reaction Steps
A mixture of 3.5 g 1H-Pyrimidine-2,4-dione and 3 g 1-Fluoro-4-nitro-benzene and 13.8 g Cs2CO3 in 60 mL DMF was heated to 80° C. for 12 h. This solution was poured on to 200 mL of water and the resulting precipitate was collected by filtration to yield a bright yellow crystalline product, which was dried under reduced pressure. Yield: 2.6 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07741341B2 |
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| Source dataset | uspto-grants-2010_06 |
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| ORD ID | ord-d6ab52a054f44054930b84bdf35417b4 |
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| Source note | uspto-grants-2010_06 |
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