反应详情

温度

80 °C

A mixture of 3.5 g 1H-Pyrimidine-2,4-dione and 3 g 1-Fluoro-4-nitro-benzene and 13.8 g Cs2CO3 in 60 mL DMF was heated to 80° C. for 12 h. This solution was poured on to 200 mL of water and the resulting precipitate was collected by filtration to yield a bright yellow crystalline product, which was dried under reduced pressure. Yield: 2.6 g.

1. filtrationthe resulting precipitate was collected by filtration
2. customto yield a bright yellow crystalline product, which
3. customwas dried under reduced pressure