HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 58956316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzenemethanamine, 3-nitro-, hydrochloride (1:1) | HCID 2724030 | — |
| Reactant | Cyclopropanesulfonyl chloride | HCID 2760919 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 58956316 | HCID 58956316 | — |
Reaction Steps
3-Nitrobenzylamine HCl (1.48 g), cyclopropanesulfonyl chloride (1 g) and triethylamine (2.98 mL) were dissolved in dichloromethane (20 mL). The reaction solution was stirred at rt overnight. The reaction mixture was diluted with 1N HCl aq. solution (50 mL) and water (100 mL). The solution was extracted with ethyl acetate (2×100 mL). The organic solution was evaporated to give N-cyclopropylsulfonyl-3-nitrobenzylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08962643B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-577a5709776241d4adcbe8a1436bc8c4 |
| Source note | uspto-grants-2015_02 |